PDRN

Polynucleotides, also known as Salmon DNA a revolutionary treatment for skin rejuvenation! This cutting-edge procedure restores
hydration, improves elasticity, and  boosts collagen for a naturally radiant glow.

What is PDRN?

PDRN (Polydeoxyribonucleotide) is a DNA-derived compound, most commonly extracted from salmon sperm DNA. It has strong regenerative and anti-inflammatory properties and is widely used in dermatology and aesthetic medicine.

It works by:

  • Activating A2A adenosine receptors

  • Stimulating fibroblast activity

  • Promoting tissue repair and collagen synthesis

 

Benefits for Skin Rejuvenation

PDRN is especially valued for skin healing and quality improvement, not volume.

Main effects:

  • Improves skin texture & elasticity

  • Enhances hydration

  • Reduces fine lines

  • Calms inflammation & redness

  • Accelerates wound healing

  • Supports post-procedure recovery (laser, RF, microneedling)

Best for:

  • Dull or tired skin

  • Thin or damaged skin

  • Acne-scarred or sensitized skin

  • Aging skin with loss of vitality


How is PDRN Used?

1. Injectable (Skin Booster / Mesotherapy)

  • Micro-injections into the dermis

  • Often called salmon DNA injections

2. Topical / Post-Procedure

  • Applied after lasers or microneedling

  • Enhances healing and reduces downtime

3. Combination Treatments

  • With microneedling

  • With laser resurfacing

  • With RF or ultrasound devices


Treatment Protocol (Typical)

  • Sessions: 3–4 treatments

  • Interval: Every 2–4 weeks

  • Maintenance: Every 3–6 months

Results are gradual and natural, improving over weeks as collagen remodeling occurs.


Safety & Side Effects

Generally very safe
Possible mild effects:

  • Temporary redness

  • Swelling

  • Small injection marks

 Avoid if:

  • Fish/salmon allergy

  • Active skin infection

  • Pregnancy (precautionary)


PDRN vs Other Injectables

TreatmentMain Purpose
PDRNSkin repair & regeneration
Hyaluronic acid fillersVolume & contour
Skin boosters (HA)Hydration
PRPGrowth factor stimulation

PDRN is ideal if your goal is skin quality, not volume.


Bottom Line

PDRN is excellent for skin rejuvenation, especially if you want:

  • Healthier, stronger skin

  • Natural improvement (not overfilled)

  • Faster recovery after aesthetic procedure

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