PDRN
Polynucleotides, also known as Salmon DNA a revolutionary treatment for skin rejuvenation! This cutting-edge procedure restores
hydration, improves elasticity, and boosts collagen for a naturally radiant glow.
What is PDRN?
PDRN (Polydeoxyribonucleotide) is a DNA-derived compound, most commonly extracted from salmon sperm DNA. It has strong regenerative and anti-inflammatory properties and is widely used in dermatology and aesthetic medicine.
It works by:
Activating A2A adenosine receptors
Stimulating fibroblast activity
Promoting tissue repair and collagen synthesis
Benefits for Skin Rejuvenation
PDRN is especially valued for skin healing and quality improvement, not volume.
Main effects:
Improves skin texture & elasticity
Enhances hydration
Reduces fine lines
Calms inflammation & redness
Accelerates wound healing
Supports post-procedure recovery (laser, RF, microneedling)
Best for:
Dull or tired skin
Thin or damaged skin
Acne-scarred or sensitized skin
Aging skin with loss of vitality
How is PDRN Used?
1. Injectable (Skin Booster / Mesotherapy)
Micro-injections into the dermis
Often called salmon DNA injections
2. Topical / Post-Procedure
Applied after lasers or microneedling
Enhances healing and reduces downtime
3. Combination Treatments
With microneedling
With laser resurfacing
With RF or ultrasound devices
Treatment Protocol (Typical)
Sessions: 3–4 treatments
Interval: Every 2–4 weeks
Maintenance: Every 3–6 months
Results are gradual and natural, improving over weeks as collagen remodeling occurs.
Safety & Side Effects
Generally very safe
Possible mild effects:
Temporary redness
Swelling
Small injection marks
Avoid if:
Fish/salmon allergy
Active skin infection
Pregnancy (precautionary)
PDRN vs Other Injectables
| Treatment | Main Purpose |
|---|---|
| PDRN | Skin repair & regeneration |
| Hyaluronic acid fillers | Volume & contour |
| Skin boosters (HA) | Hydration |
| PRP | Growth factor stimulation |
PDRN is ideal if your goal is skin quality, not volume.
Bottom Line
PDRN is excellent for skin rejuvenation, especially if you want:
Healthier, stronger skin
Natural improvement (not overfilled)
Faster recovery after aesthetic procedure

